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1

Mechanisms underlying the dualistic mode of action of major soy isoflavones in relation to cell proliferation and cancer risks

Rietjens, Ivonne M. C. M., Sotoca, Ana M., Vervoort, Jacques, Louisse, Jochem

Journal:

Molecular Nutrition & Food Research

Année:

2013

Langue:

english

Fichier:

PDF, 629 KB

english, 2013

2

Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling

Louisse, Jochem, Bosgra, Sieto, Blaauboer, Bas J., Rietjens, Ivonne M. C. M., Verwei, Miriam

Journal:

Archives of Toxicology

Année:

2015

Langue:

english

Fichier:

PDF, 805 KB

english, 2015

3

The potential health effects of dietary phytoestrogens

Rietjens, Ivonne M.C.M., Louisse, Jochem, Beekmann, Karsten

Journal:

British Journal of Pharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 739 KB

english, 2016

4

Use of physiologically based kinetic modeling-based reverse dosimetry to predict in vivo toxicity from in vitro data

Louisse, Jochem, Beekmann, Karsten, Rietjens, Ivonne Magdalena Catharina Maria

Journal:

Chemical Research in Toxicology

Année:

2016

Langue:

english

Fichier:

PDF, 806 KB

english, 2016

5

Exploration of ToxCast/Tox21 bioassays as candidate bioanalytical tools for measuring groups of chemicals in water

Louisse, Jochem, Dingemans, Milou M.L., Baken, Kirsten A., van Wezel, Annemarie P., Schriks, Merijn

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2018

6

Tutorial on physiologically based kinetic modeling in molecular nutrition and food research

Ivonne M. C. M. Rietjens, Jochem Louisse, Ans Punt

Journal:

Molecular Nutrition & Food Research

Année:

2011

Langue:

english

Fichier:

PDF, 417 KB

english, 2011

7

Relative developmental toxicity of glycol ethers in the embryonic stem cell test and comparison to their in vivo potency ranking

Esther de Jong, Jochem Louisse, Miriam Verwei, Bas J. Blaauboer, Han van de Sandt, Ruud A. Woutersen, Ivonne M. Rietjens, Aldert H. Piersma

Journal:

Reproductive Toxicology

Année:

2009

Langue:

english

Fichier:

PDF, 58 KB

english, 2009

8

Decrease of intracellular pH as possible mechanism of embryotoxicity of glycol ether alkoxyacetic acid metabolites

Jochem Louisse, Yanqing Bai, Miriam Verwei, Johannes J.M. van de Sandt, Bas J. Blaauboer, Ivonne M.C.M. Rietjens

Journal:

Toxicology and Applied Pharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 917 KB

english, 2010

9

Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation

Louisse, Jochem, Verwei, Miriam, Woutersen, Ruud A, Blaauboer, Bas J, Rietjens, Ivonne MCM

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2012

Langue:

english

Fichier:

PDF, 653 KB

english, 2012

10

Relative developmental toxicity potencies of retinoids in the embryonic stem cell test compared with their relative potencies in in vivo and two other in vitro assays for developmental toxicity

Jochem Louisse, Süleyman Gönen, Ivonne M.C.M. Rietjens, Miriam Verwei

Journal:

Toxicology Letters

Année:

2011

Langue:

english

Fichier:

PDF, 289 KB

english, 2011

11

Estrogenic Potency of Food-Packaging-Associated Plasticizers and Antioxidants As Detected in ERα and ERβ Reporter Gene Cell Lines

ter Veld, Marcel G. R., Schouten, Bastiaan, Louisse, Jochem, van Es, Daan S., van der Saag, Paul T., Rietjens, Ivonne M. C. M., Murk, Albertinka J.

Journal:

Journal of Agricultural and Food Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 593 KB

english, 2006

12

Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: Effects of CREB pathway inhibition

Pistollato, Francesca, Louisse, Jochem, Scelfo, Bibiana, Mennecozzi, Milena, Accordi, Benedetta, Basso, Giuseppe, Gaspar, John Antonydas, Zagoura, Dimitra, Barilari, Manuela, Palosaari, Taina, Sachini

Journal:

Toxicology and Applied Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 4.27 MB

english, 2014

13

Quantitative in vitro to in vivo extrapolation of stem cell-based toxicity data to predict developmental toxicity dose levels

Louisse, Jochem

Journal:

Toxicology Letters

Année:

2014

Langue:

english

Fichier:

PDF, 54 KB

english, 2014

14

Regenerative toxicology: the role of stem cells in the development of chronic toxicities

Canovas-Jorda, David, Louisse, Jochem, Pistollato, Francesca, Zagoura, Dimitra, Bremer, Susanne

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2014

Langue:

english

Fichier:

PDF, 301 KB

english, 2014

15

Use of the ES-D3 cell differentiation assay, combined with the BeWo transport model, to predict relative in vivo developmental toxicity of antifungal compounds

Li, Hequn, Rietjens, Ivonne M.C.M., Louisse, Jochem, Blok, Martine, Wang, Xinyi, Snijders, Linda, van Ravenzwaay, Bennard

Journal:

Toxicology in Vitro

Année:

2015

Langue:

english

Fichier:

PDF, 546 KB

english, 2015

16

Putative adverse outcome pathways relevant to neurotoxicity

Bal-Price, Anna, Crofton, Kevin M., Sachana, Magdalini, Shafer, Timothy J., Behl, Mamta, Forsby, Anna, Hargreaves, Alan, Landesmann, Brigitte, Lein, Pamela J., Louisse, Jochem, Monnet-Tschudi, Florian

Journal:

Critical Reviews in Toxicology

Année:

2015

Langue:

english

Fichier:

PDF, 384 KB

english, 2015

17

Regulation of P-Glycoprotein in Renal Proximal Tubule Epithelial Cells by LPS and TNF-α

Heemskerk, Suzanne, Peters, Janny G. P., Louisse, Jochem, Sagar, Seil, Russel, Frans G. M., Masereeuw, Rosalinde

Journal:

Journal of Biomedicine and Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 910 KB

english, 2010

18

Role of environmental chemicals, processed food derivatives and nutrients in the induction of carcinogenesis

Persano, Luca, Zagoura, Dimitra, Louisse, Jochem, Pistollato, Francesca

Journal:

Stem Cells and Development

Année:

2015

Langue:

english

Fichier:

PDF, 563 KB

english, 2015

19

Extended evaluation on the ES-D3 cell differentiation assay combined with the BeWo transport model, to predict relative developmental toxicity of triazole compounds

Li, Hequn, Flick, Burkhard, Rietjens, Ivonne M. C. M., Louisse, Jochem, Schneider, Steffen, van Ravenzwaay, Bennard

Journal:

Archives of Toxicology

Année:

2016

Langue:

english

Fichier:

PDF, 526 KB

english, 2016

20

Translocation of positively and negatively charged polystyrene nanoparticles in an in vitro placental model

Kloet, Samantha K., Walczak, Agata P., Louisse, Jochem, van den Berg, Hans H.J., Bouwmeester, Hans, Tromp, Peter, Fokkink, Remco G., Rietjens, Ivonne M.C.M.

Journal:

Toxicology in Vitro

Année:

2015

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2015

21

Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment

Chaudhari, Umesh, Nemade, Harshal, Wagh, Vilas, Gaspar, John Antonydas, Ellis, James K., Srinivasan, Sureshkumar Perumal, Spitkovski, Dimitry, Nguemo, Filomain, Louisse, Jochem, Bremer, Susanne, Hesch

Journal:

Archives of Toxicology

Année:

2016

Langue:

english

Fichier:

PDF, 3.37 MB

english, 2016

22

In vitro developmental toxicity potencies of petroleum substances in the embryonic stem cell test as compared to their in vivo developmental toxicity potencies

Kamelia, Lenny, Louisse, Jochem, Rietjens, Ivonne M.C.M., Boogaard, Peter J.

Journal:

Reproductive Toxicology

Année:

2016

Langue:

english

Fichier:

PDF, 98 KB

english, 2016

23

Use of physiologically based kinetic modeling-facilitated reverse dosimetry of in vitro toxicity data for prediction of in vivo developmental toxicity of tebuconazole in rats

Li, Hequn, Zhang, Mengying, Vervoort, Jacques, Rietjens, Ivonne M.C.M., van Ravenzwaay, Bennard, Louisse, Jochem

Journal:

Toxicology Letters

Année:

2016

Langue:

english

Fichier:

PDF, 568 KB

english, 2016

24

Risk assessment for pyrrolizidine alkaloids detected in (herbal) teas and plant food supplements

Chen, Lu, Mulder, Patrick P.J., Louisse, Jochem, Peijnenburg, Ad, Wesseling, Sebas, Rietjens, Ivonne M.C.M.

Journal:

Regulatory Toxicology and Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2017

25

Assessment of acute and chronic toxicity of doxorubicin in human induced pluripotent stem cell-derived cardiomyocytes

Louisse, Jochem, Wüst, Rob C.I., Pistollato, Francesca, Palosaari, Taina, Barilari, Manuela, Macko, Peter, Bremer, Susanne, Prieto, Pilar

Journal:

Toxicology in Vitro

Année:

2017

Langue:

english

Fichier:

PDF, 890 KB

english, 2017

26

In vitro bioassays to evaluate beneficial and adverse health effects of botanicals: promises and pitfalls

Prinsloo, Gerhard, Papadi, Georgia, Hiben, Mebrahtom G., de Haan, Laura, Louisse, Jochem, Beekmann, Karsten, Vervoort, Jacques, Rietjens, Ivonne M.C.M.

Journal:

Drug Discovery Today

Année:

2017

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2017

27

Study on inter-ethnic human differences in bioactivation and detoxification of estragole using physiologically based kinetic modeling

Ning, Jia, Louisse, Jochem, Spenkelink, Bert, Wesseling, Sebastiaan, Rietjens, Ivonne M. C. M.

Journal:

Archives of Toxicology

Année:

2017

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2017

28

A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling

Mengeling, Brenda J., Wei, Yuzhu, Dobrawa, Lucia N., Streekstra, Mischa, Louisse, Jochem, Singh, Vikrant, Singh, Latika, Lein, Pamela J., Wulff, Heike, Murk, Albertinka J., Furlow, J. David

Journal:

Aquatic Toxicology

Année:

2017

Langue:

english

Fichier:

PDF, 759 KB

english, 2017

29

Characterization of the differential coregulator binding signatures of the Retinoic Acid Receptor subtypes upon (ant)agonist action

Miro Estruch, Ignacio, Melchers, Diana, Houtman, René, de Haan, Laura H.J., Groten, John P., Louisse, Jochem, Rietjens, Ivonne M.C.M.

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2017

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2017

30

Prenatal developmental toxicity testing of petroleum substances: Application of the mouse embryonic stem cell test (EST) to compare in vitro potencies with potencies observed in vivo

Kamelia, Lenny, Louisse, Jochem, de Haan, Laura, Rietjens, Ivonne M.C.M., Boogaard, Peter J.

Journal:

Toxicology in Vitro

Année:

2017

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2017

31

The role of metabolism in the prenatal developmental toxicity (PDT) of polycyclic aromatic hydrocarbons (PAHs) in petroleum substances

Kamelia, Lenny, Louisse, Jochem, Rietjens, Ivonne M.C.M., Boogaard, Peter J.

Journal:

Reproductive Toxicology

Année:

2017

Langue:

english

Fichier:

PDF, 54 KB

english, 2017

32

Virtual Cell Based Assay simulations of intra-mitochondrial concentrations in hepatocytes and cardiomyocytes

Worth, Andrew P., Louisse, Jochem, Macko, Peter, Sala Benito, Jose Vicente, Paini, Alicia

Journal:

Toxicology in Vitro

Année:

2017

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2017

33

Towards a generic physiologically based kinetic model to predict in vivo uterotrophic responses in rats by reverse dosimetry of in vitro estrogenicity data

Zhang, Mengying, van Ravenzwaay, Bennard, Fabian, Eric, Rietjens, Ivonne M. C. M., Louisse, Jochem

Journal:

Archives of Toxicology

Année:

2017

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2017

34

Development and application of an adverse outcome pathway for cardiotoxicity

Louisse, Jochem, Prior, Helen

Journal:

Toxicology Letters

Année:

2017

Langue:

english

Fichier:

PDF, 44 KB

english, 2017

35

The effects of all-trans retinoic acid on estrogen receptor signaling in the estrogen-sensitive MCF/BUS subline

Miro Estruch, Ignacio, de Haan, Laura H. J., Melchers, Diana, Houtman, René, Louisse, Jochem, Groten, John P., Rietjens, Ivonne M. C. M.

Journal:

Journal of Receptor and Signal Transduction Research

Année:

2018

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2018

36

Use of physiologically based kinetic modelling-facilitated reverse dosimetry to convert in vitro cytotoxicity data to predicted in vivo liver toxicity of lasiocarpine and riddelliine in rat

Chen, Lu, Ning, Jia, Louisse, Jochem, Wesseling, Sebas, Rietjens, Ivonne M.C.M.

Journal:

Food and Chemical Toxicology

Année:

2018

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2018

37

The Role of Endocrine and Dioxin-Like Activity of Extracts of Petroleum Substances in Developmental Toxicity as Detected in a Panel of CALUX Reporter Gene Assays

Kamelia, Lenny, Louisse, Jochem, de Haan, Laura, Maslowska-Gornicz, Anna, Ketelslegers, Hans B, Brouwer, Abraham, Rietjens, Ivonne M C M, Boogaard, Peter J

Journal:

Toxicological Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 1012 KB

english, 2018

38

Biomonitoring and Subsequent Risk Assessment of Combined Exposure to Phthalates in Iranian Children and Adolescents

Zare Jeddi, Maryam, Eshaghi Gorji, Mohamad, Rietjens, Ivonne, Louisse, Jochem, Bruinen de Bruin, Yuri, Liska, Roman

Journal:

International Journal of Environmental Research and Public Health

Année:

2018

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2018

39

Selecting the dose metric in reverse dosimetry based QIVIVE

Rietjens, Ivonne M. C. M., Ning, Jia, Chen, Lu, Wesseling, Sebastiaan, Strikwold, Marije, Louisse, Jochem

Journal:

Archives of Toxicology

Année:

2019

Langue:

english

Fichier:

PDF, 357 KB

english, 2019

40

Selecting the dose metric in reverse dosimetry based QIVIVE

Rietjens, Ivonne M. C. M., Ning, Jia, Chen, Lu, Wesseling, Sebastiaan, Strikwold, Marije, Louisse, Jochem

Journal:

Archives of Toxicology

Année:

2019

Fichier:

PDF, 357 KB

2019

41

Determination of genotoxic potencies of pyrrolizidine alkaloids in HepaRG cells using the γH2AX assay

Louisse, Jochem, Rijkers, Deborah, Stoopen, Geert, Holleboom, Wendy Jansen, Delagrange, Mona, Molthof, Elise, Mulder, Patrick P.J., Hoogenboom, Ron L.A.P., Audebert, Marc, Peijnenburg, Ad A.C.M.

Journal:

Food and Chemical Toxicology

Année:

2019

Langue:

english

Fichier:

PDF, 5.50 MB

english, 2019

42

The in vivo developmental toxicity of diethylstilbestrol (DES) in rat evaluated by an alternative testing strategy

Adam, Aziza Hussein Bakheit, Zhang, Mengying, de Haan, Laura H. J., van Ravenzwaay, Bennard, Louisse, Jochem, Rietjens, Ivonne M. C. M.

Journal:

Archives of Toxicology

Année:

2019

Fichier:

PDF, 1011 KB

2019

43

Ethnomedicine and ethnobotany of Maerua subcordata (Gilg) DeWolf

Hiben, Mebrahtom Gebrelibanos, Louisse, Jochem, de Haan, Laura H.J., Rietjens, Ivonne M. C. M.

Journal:

Journal of Ethnic Foods

Année:

2019

Fichier:

PDF, 824 KB

2019

44

Estrogen receptor alpha (ERÎ±)âmediated coregulator binding and gene expression discriminates the toxic ERÎ± agonist diethylstilbestrol (DES) from the endogenous ERÎ± agonist 17Î²-estradiol (E2)

Adam, Aziza Hussein Bakheit, de Haan, Laura H. J., Estruch, Ignacio Miro, Hooiveld, Guido J. E. J., Louisse, Jochem, Rietjens, Ivonne M. C. M.

Journal:

Cell Biology and Toxicology

Année:

2020

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2020

45

Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells

Louisse, Jochem, Rijkers, Deborah, Stoopen, Geert, Janssen, Aafke, Staats, Martijn, Hoogenboom, Ron, Kersten, Sander, Peijnenburg, Ad

Journal:

Archives of Toxicology

Année:

2020

Fichier:

PDF, 2.90 MB

2020

46

Defining in vivo doseâresponse curves for kidney DNA adduct formation of aristolochic acid I in rat, mouse and human by an in vitro and physiologically based kinetic modeling approach

Abdullah, Rozaini, Wesseling, Sebastiaan, Spenkelink, Bert, Louisse, Jochem, Punt, Ans, Rietjens, Ivonne M.C.M.

Journal:

Journal of Applied Toxicology

Année:

2020

Fichier:

PDF, 806 KB

2020

47

Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells and Caco-2 cells

Janssen, Aafke W. F., Duivenvoorde, Loes P. M., Rijkers, Deborah, Nijssen, Rosalie, Peijnenburg, Ad A. C. M., van der Zande, Meike, Louisse, Jochem

Journal:

Archives of Toxicology

Année:

2020

Fichier:

PDF, 6.68 MB

2020

48

Organophosphate and carbamate pesticide residues and accompanying risks in commonly consumed vegetables in Kenya

Omwenga, Isaac, Kanja, Laetitia, Zomer, Paul, Louisse, Jochem, Rietjens, Ivonne M.C.M., Mol, Hans

Journal:

Food Additives and Contaminants Part B

Année:

2020

Fichier:

PDF, 599 KB

2020